Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960 -16-0 (net) / 60189-34-6 (acetate)

Model NO.
16960-16-0
Package
Drum or Bottle
Express
Special Line, FedEx, UPS
Keyword 2
Cosyntropin
MOQ
1kit
Keyword 1
16960-16-0
Transport Package
10vials Per Box
Specification
10vials Per Box
Origin
China
Production Capacity
100000vials/Month
Reference Price
$ 9.00 - 45.00

Product Description

Product Name:Tetracosactide,Cosyntropin,Tetracosactrin,acortan
Alias: AC TH (1-24), HUMAN; AC TH (1-24) (HUMAN, BOVINE, MOUSE, OVINE, PORCINE, RABBIT, RAT); AC TH (1-24);
Purity: 99%
CAS Registry Number: 16960-16-0
Einecs No: 241-031-1
MF: C136H210N40O31S
MW: 2933.47
Melting point: 2 ° C
Boiling point: 225° C
Refractive index: 1.551-1.553
Appearance: White powder
Grade: Pharmceutical Grade
Storage: Shading, confined preservation
Usage: Cosyntropin (cortrosyn) is a synthetic derivative of adrenocorticotropic hormone (AC TH) that is used in the AC TH stimulation test to evaluate and diagnose cortisol disorders.

 
Synonyms Tetracosactide Acetate
CAS No. 60189-34-6
Appearance white powder
Application Pharma grade or research purpose
Packing As per your request
Storage Preserve in tight,light-resistant containers in a cool place
Remarks NA

Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. AC TH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same activity as natural AC TH with regard to all its biological activities. The complex results in a product whose absorption in man is effected over a longer period of time as compared to corticotropin. Therefore, therapy may be maintained with less frequent administration.

Product Usage

Cosyntropin exhibits the full corticosteroidogenic activity of natural AC TH. Various studies have shown that the biologic activity of AC TH resides in the N- terminal portion of the molecule and that the 1-20 amino acid residue is the minimal sequence retaining full activity. Partial or complete loss of activity is noted with progressive shortening of the chain beyond 20 amino acid residue. For example, the decrement from 20 to 19 results in a 70% loss of potency. The pharmacologic profile of Cosyntropin is similar to that of purified natural AC TH. It has been established that 0.25 mg of Cosyntropin will stimulate the adrenal cortex maximally and to the same extent as 25 units of natural AC TH. Cosyntropin has less immunogenic activity than AC TH because the amino acid sequence having most of the antigenic activity of AC TH, i.e., amino acids 25-39, is not present in cosyntropin. The extra-adrenal effects which natural AC TH and Cosyntropin have in common include increased melanotropic activity, increased grow hormone secretion and an adipokinetic effect. These are considered to be without physiological or clinical significance.

 

Detailed Photos

 

Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
 

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Company Profile

Dongdu biology co., ltd   is a professional production of Chemical Products.   The company was established in 2000, the company actively explore overseas markets. The company's main products are   Procain e,Pmk,Xylazine HCl,Tianeptine Sodium Salt,BMK,PMK,Lidocain e,(2-Bromoethyl)Benzene,Pharmaceutical Intermediates,Chemical Raw Materials,Iodine  The products are mainly exported to North America, South USA, Europe, Australia, the Middle East, Southeast Asia Africa, etc..

Our company mainly production workshop covers an area of 16000 square meters, 10000 square meters factory in.   We are from China and the top machinery imported from domestic manufacturers of machinery and equipment, facilities.   To ensure the quality of products, we are constantly updating our equipment and new equipment.

As we built, we keep "quality policy, the pursuit of perfection, sincere service".   Through this policy, we provide high quality products and the best service for customers.   Our goal is to make progress, with the best value for their money to our customers.   As a result, we have gained great reputation from our customers.

We welcome you warmly inquiries.   We guarantee, sincere service, high quality products and competitive price.
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)

Peptide Synthesis

Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
GMP peptides Manufacturing

Dongdu Biology has mastered the development and production of peptides for a long time. Peptides are short-chain amino acids linked by peptide bonds, which enables the new generation of small molecular drugs to closely simulate the natural pathway of human body.
Now, Dongdu Bio has a first-class industrial-scale polypeptide production capacity, which fully meets the most stringent good manufacturing practices (cGMP) standards.

Upstream peptide synthesis
Dongdu Bio's production plant has the most advanced equipment for solvent supply, peptide synthesis, purification and separation of active components and intermediates. All equipment and containers have passed GMP certification and cleaning verification. The overlapping capacity and size of different equipment series contribute to the steady growth of demand during the product life cycle.
For a wide range of liquid chemistry, Dongdu Bio uses reactors up to 5000 liters. For solid-phase peptide synthesis (SPPS), it uses a reactor up to 1000 liters, and is currently building a larger-scale selection.
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
Downstream purification and separation of peptides
Dongdu Bio is committed to the systematic expansion and modernization of purification equipment to ensure the efficient production of increasing polypeptide raw materials.
It uses complex methods for large-scale purification, such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size exclusion chromatography (SEC) and ultrafiltration (UF/TFF). After the equipment is in place, it can efficiently or even continuously produce ultra-high purity products up to several kilograms per batch.
For preparative HPLC, a dynamic axial compression (DAC) stainless steel column with a diameter of up to 60 cm was packed with a suitable high-efficiency silica gel separation phase in batch and continuous mode. For low-pressure chromatographic columns, the diameter can reach 80 cm. Ensure that the solvent is transported from the eluent storage tank area and containers.
The control of microbial contamination is a prerequisite for the production of APIs. Class D (ISO 8) and Class C (ISO 7) cleanrooms are supplied with HEPA filtered air with controlled temperature and humidity. Downflow cleanrooms are used to minimize microbial pollution and protect operators. Highly active pharmaceutical ingredients are processed in an integrated safety workbench or flexible isolator that reaches OEB 4 level (1-10 g/m3).
The predefined physical and chemical properties of APIs can only be achieved through strictly controlled separation processes. In addition to precipitation and crystallization, lyophilization of intermediates and final APIs is a standard unit operation. Dongdu Bio has several freeze-dryers of different sizes (up to 300 liters) in the clean room.
Small molecule manufacturing
Dongdu Bio's peptide factory also provides a series of professional services for the production of cGMP small molecules.
Small molecule production capacity includes: process development, chiral synthesis, heterocyclic chemistry, metal catalytic reaction, hydrogenation, oxidation and reduction using various reagents, enzymatic reaction and high pressure reaction.
Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)
 

Certifications

Lab-Tested 99% Medical Pharmaceutical Peptide Cosyntropin / Tetracosactide Acetate CAS 16960-16-0 (net) / 60189-34-6 (acetate)

 

Packaging & Shipping

Our Advantages

1. Quality
Our products meet msds safe standard and we have iso and other certificate so yan can get high quality products from our company.

2.  Price
We are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.

3. Packing
We can do according to the customers' request.

4. Transport
EMS, DHL, TNT, UPS ,FEDEX, by air, by sea
DHL express, FEDEX and EMS for quantity less than 50kg, usually called as ddu service; 
sea shipping for quantity over 500kg; and air shipping is available for 50kg above;
for high value products, please select air shipping and DHL express for safe;

5. Service
we offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.

 

FAQ

Q1: Can you supply samples?
Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.

Q2:What's the MOQ?
Differentiate according to the product value,1 gram or 50 kilograms and 100 kilograms.

Q3. How can I release the payment to you ?
We can receive your payment by T/T, ESCROW or Western union which is recommended, and we can also receive by L/C at sight.

Q4:How about delivery leadtime ?
About 3-5 working days after receipt of  your payment.

Q5:Is there a discount?
Yes, for large quantity, we always support with better price

Q6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q7:How to confirm the Product Quality before placing orders?
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests








 

 

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