Synonyms | Tetracosactide Acetate |
CAS No. | 60189-34-6 |
Appearance | white powder |
Application | Pharma grade or research purpose |
Packing | As per your request |
Storage | Preserve in tight,light-resistant containers in a cool place |
Remarks | NA |
Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. AC TH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same activity as natural AC TH with regard to all its biological activities. The complex results in a product whose absorption in man is effected over a longer period of time as compared to corticotropin. Therefore, therapy may be maintained with less frequent administration.
Cosyntropin exhibits the full corticosteroidogenic activity of natural AC TH. Various studies have shown that the biologic activity of AC TH resides in the N- terminal portion of the molecule and that the 1-20 amino acid residue is the minimal sequence retaining full activity. Partial or complete loss of activity is noted with progressive shortening of the chain beyond 20 amino acid residue. For example, the decrement from 20 to 19 results in a 70% loss of potency. The pharmacologic profile of Cosyntropin is similar to that of purified natural AC TH. It has been established that 0.25 mg of Cosyntropin will stimulate the adrenal cortex maximally and to the same extent as 25 units of natural AC TH. Cosyntropin has less immunogenic activity than AC TH because the amino acid sequence having most of the antigenic activity of AC TH, i.e., amino acids 25-39, is not present in cosyntropin. The extra-adrenal effects which natural AC TH and Cosyntropin have in common include increased melanotropic activity, increased grow hormone secretion and an adipokinetic effect. These are considered to be without physiological or clinical significance.
Generic Peptides | CAS No . | Application |
Semaglutide | 910463-68-2 | Diabetes Mellitus |
Liraglutide | 204656-20-2 | Diabetes Mellitus |
Albiglutide | 782500-75-8 | Diabetes Mellitus |
Beinaglutide | 123475-27-4 | Dlabetes Mellitus |
Dulaglutide | 923950-08-7 | Diabetes Mellitus |
Exenatide | 141732-76-5 | Diabetes Mellitus |
Lixisenatide | 320367- 13-3 | Diabetes Mellitus |
Tirzepatide | 2023788- 19-2 | Diabetes Mellitus & others |
( Arg 8)- Vasopressin | 11000- 17-2 | Diabetes Insipidus |
Abarelix (acetate) | 183552-38-7 | Oncology |
Alarelin Acetate (GnRH a gonist) | 79561-22- 1 | Women's health |
Bivalirudin (trifluor oacetate) | 128270-60-0( net ) | Cardiovascular Disease |
1607799- 13-2 ( acetate ) | Male health | |
Busereli | 57982-77- 1 ( net ) | Oncology, Reproductive Medicine |
68630-75- 1 ( acetate ) | ||
Calcitonin (salmon) | 47931-85- 1 | Paget's disease, Hyp ercalcemnia and Osteoporosis |
Carbetocin Acetate | 37025-55- 1 | Women's health |
Copper Peptide GHK-Cu (acetate) | 300801-03-0 | Anti-aging |
Degarelix | 214766-78-6 | Prostatic diseases |
DSIP Delta sleep-inducin g peptide | 62568-57-4 | |
Epithalon | Anti-aging | |
Glucagon | 16941-32-5 | Diabetes Mellitus |
Gonadoreli Acetate | 33515-09-2 ( net ) | Oncology, Reproductive Medicine |
34973-08-5 ( acetate ) | ||
Goserelim Acetate | 65807-02-5 ( net ) | Oncology, Reproductive Medicine |
145781-92-6 ( acetate ) | ||
Icatibant Acetate | 130308-48-4( net ) | Hereditary Angioedema |
138614-30-9 ( acetate ) | ||
Kisspeptin ( KP - 10) | 374675-21-5 | Cancer & Apoptosis, Hormones, Neuroscience |
Leuprolide; Leuprore li n Acetate | 53714- ·56-0 ( net ) | Oncology |
74381-53-6 ( acetate ) | ||
Melanotan II | 121062-08-6 | Male bealth |
Nafareli n | 86220-42-0 | Women's health |
Octreotide (acetate) | 83150-76-9 ( net ) | Oncology |
79517-01-4 ( acetate ) | ||
Oxytocin Acetate | 6233-83·6 | Cardiovascular Disease |
Pentagastrin | 5534-95-2 | Gastrointestinal |
Pramlintide (acetate hydrate) | 196078-30-5 | Diabetes Mellitus |
Selank ( acetate ) | 129954-34-3 | Immunology |
Semax ACT H (4-7) | 80714-61-0 | Nootropics |
Seractide ( ACT H ( 1-39) Porcine ) | 12279-41-3 | Immunology |
Sincalide | 25126-32-3 | Gallbladder diseases |
Somatostatin (acetate) | 38916-34-6 ( net ) | Gastrointestinal |
Taltirelin ( TA -5910) | 1549593-23-8 | SCD |
Teduglutide | 197922-42-2 | SBS |
Teriparatide pTH ( 1-34) Acetate | 52232-67-4 ( net ) | Osteoporosis |
99294-94-7 ( acetate ) | ||
Tetracosactide (Cosyn tropin) | 16960- 16-0 (net) | Oncology, Diagnostics |
60189-34-6( acetate ) | ||
Thymalfasin ; Thymosin Alpha - 1 ( acetate ) | 62304-98-7 | CHB; Immunology |
Thymopentin TP -5 ( acetate ) | 69558-55-0 | Immunology |
Thymosin Beta -4 ( acetate ) | 77591-33/4 | Oncology |
Vyleesi (acetate) | 1607799- 13-2 | Women's health |
Setmelanotide |
Dongdu biology co., ltd
is a professional production of Chemical Products.
The company was established in 2000, the company actively explore overseas markets.
The company's main products are
Procain e,Pmk,Xylazine HCl,Tianeptine Sodium Salt,BMK,PMK,Lidocain e,(2-Bromoethyl)Benzene,Pharmaceutical Intermediates,Chemical Raw Materials,Iodine
The products are mainly exported to North America, South USA, Europe, Australia, the Middle East, Southeast Asia Africa, etc..
Our company mainly production workshop covers an area of 16000 square meters, 10000 square meters factory in.
We are from China and the top machinery imported from domestic manufacturers of machinery and equipment, facilities.
To ensure the quality of products, we are constantly updating our equipment and new equipment.
As we built, we keep "quality policy, the pursuit of perfection, sincere service".
Through this policy, we provide high quality products and the best service for customers.
Our goal is to make progress, with the best value for their money to our customers.
As a result, we have gained great reputation from our customers.
We welcome you warmly inquiries.
We guarantee, sincere service, high quality products and competitive price.
1. Quality
Our products meet msds safe standard and we have iso and other certificate so yan can get high quality products from our company.
2. Price
We are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
3. Packing
We can do according to the customers' request.
4. Transport
EMS, DHL, TNT, UPS ,FEDEX, by air, by sea
DHL express, FEDEX and EMS for quantity less than 50kg, usually called as ddu service;
sea shipping for quantity over 500kg; and air shipping is available for 50kg above;
for high value products, please select air shipping and DHL express for safe;
5. Service
we offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
Q1: Can you supply samples?
Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
Q2:What's the MOQ?
Differentiate according to the product value,1 gram or 50 kilograms and 100 kilograms.
Q3. How can I release the payment to you ?
We can receive your payment by T/T, ESCROW or Western union which is recommended, and we can also receive by L/C at sight.
Q4:How about delivery leadtime ?
About 3-5 working days after receipt of your payment.
Q5:Is there a discount?
Yes, for large quantity, we always support with better price
Q6:How do you treat quality complaint?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q7:How to confirm the Product Quality before placing orders?
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests